Efficiency of Hyperbaric Oxygen Therapy in the Treatment of Carbon Monoxide Toxicity.

A 41-year-old male presented with carbon monoxide (CO) exposure. The patient’s Glasgow Coma Scale (GCS) score was 9. Dual-energy CT (DECT) revealed a perfusion defect on the bilateral globus pallidus (Figure 1a). The patient was intubated and immediately underwent hyperbaric oxygen therapy (HBOT). In addition to normobaric oxygen therapy, two sessions on the first day and one session each on the second, third, and fourth days of HBOT were performed. DECT was performed on the fifth day of hospitalization after HBOT was completed. Control DECT showed a decrease in iodine uptake and relative recovery in perfusion in the bilateral globus pallidus (Figure 1b). After HBOT sessions, the following results were observed: GCS: before treatment, 9 and after treatment, 15; COHb level: before treatment, 55.1% and after treatment, 5.3%; MetHb level: before treatment, 1.9% and after treatment, 1.1%.